資料來源:https://www.nationalgeographic.co.uk/science-and-technology/2022/12/can-ageing-be-cured-scientists-are-giving-it-a-try
Can ageing be cured? Scientists are giving it a try
BY FRAN SMITH
PUBLISHED 29 DEC 2022, 13:53 GMT
Scientists are great at making mice live longer.
Rapamycin, widely prescribed to prevent organ rejection after a transplant, increases the life expectancy of middle-age mice by as much as 60 percent. Drugs called senolytics help geriatric mice stay sprightly long after their peers have died. The diabetes drugs metformin and acarbose, extreme calorie restriction, and, by one biotech investor’s count, about 90 other interventions keep mice skittering around lab cages well past their usual expiration date. The newest scheme is to hack the ageing process itself by reprogramming old cells to a younger state.
Scientists are great at making mice live longer.
Rapamycin, widely prescribed to prevent organ rejection after a transplant, increases the life expectancy of middle-age mice by as much as 60 percent. Drugs called senolytics help geriatric mice stay sprightly long after their peers have died. The diabetes drugs metformin and acarbose, extreme calorie restriction, and, by one biotech investor’s count, about 90 other interventions keep mice skittering around lab cages well past their usual expiration date. The newest scheme is to hack the ageing process itself by reprogramming old cells to a younger state.
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